Prenatal inflammation and lung development
نویسندگان
چکیده
منابع مشابه
Prenatal Lung Development
Lung development requires integration of multiple regulatory factors that mediate patterns of cell proliferation, differentiation, migration, and death. These developmental programs, which include transcription factors and signaling molecules, are likely re-enlisted during recovery of the lung following injury. Understanding these processes could provide important insight into controlling cell ...
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Bronchopulmonary dysplasia (BPD) is a major cause of mortality and long-term morbidity in prematurely born infants. Pulmonary inflammation, and abnormal alveolar and vascular development of the lung are histological characteristics of BPD. Interleukin (IL)-1β is a central cytokine in inflammation. Increased concentration of IL-1β in amniotic fluid or postnatally in the lungs of newborn infants ...
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A growing body of evidence indicates that the epithelial-specific growth factors keratinocyte growth factor (KGF), fibroblast growth factor (FGF)-10, and hepatocyte growth factor (HGF) play important roles in lung development, lung inflammation, and repair. The therapeutic potential of these growth factors in lung disease has yet to be fully explored. KGF has been best studied and has impressiv...
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ژورنال
عنوان ژورنال: Seminars in Fetal and Neonatal Medicine
سال: 2009
ISSN: 1744-165X
DOI: 10.1016/j.siny.2008.08.011